Our group has conducted numerous reviews designed to help veterinarians and producers to make evidence based animal health decisions about the choice of vaccines and treatment options, these are listed by species below.

Swine Health

Powell, M.J., Yuan, C., Dzikamunhenga, R.S., Tarté, R., Huff-Lonergan, E., Lonergan, S.M. and O’Connor, A.M., 2017. A systematic review and meta-analysis of tenderness metrics in control groups used in comparative nutrition experiments. Translational Animal Science.

Mixed treatment comparison meta-analysis of porcine circovirus type 2 (PCV2) vaccines used in piglets. da Silva N, Carriquiry A, O’Neill K, Opriessnig T, O’Connor AM. Prev Vet Med. 2014 Dec 1;117(3-4):413-24. doi: 10.1016/j.prevetmed.2014.10.006. Epub 2014 Oct 31. PMID: 25457512
Video introduction to MTC paper

Letter to editor: Meta-analysis of porcine circovirus type 2 (PCV2) vaccines. Allison JR, Nitzel GP, Taylor LP. Prev Vet Med. 2015 Jan 28. pii: S0167-5877(15)00028-8. doi: 10.1016/j.prevetmed.2015.01.012. No abstract available.

Response to Allison et al. ‘Meta-analysis of porcine circovirus type 2 (PCV2) vaccines’ da Silva N, Carriquiry A, O’Neill K, Opriessnig T, O’Connor AM. Prev Vet Med. 2015 Feb 7. pii: S0167-5877(15)00027-6. doi: 10.1016/j.prevetmed.2015.01.011.

Dzikamunhenga RS, Anthony R, Coetzee J, Gould S, Johnson A, Karriker L, McKean J, Millman ST, Niekamp SR, O’Connor AM. Pain management in the neonatal piglet during routine management procedures. Part 1: a systematic review of randomized and non-randomized intervention studies. Animal Health Research Reviews. 2014;15(01):14-38. doi: doi:10.1017/S1466252314000061.
Video introduction to the pain mitigation paper

O’Connor A, Anthony R, Bergamasco L, Coetzee J, Gould S, Johnson AK, Karriker LA, Marchant-Forde JN, Martineau GS, McKean J, Millman ST, Niekamp S, Pajor EA, Rutherford K, Sprague M, Sutherland M, von Borell E, Dzikamunhenga RS. Pain management in the neonatal piglet during routine management procedures. Part 2:Grading the quality of evidence and the strength of recommendations. Animal Health Research Reviews. 2014;15(01):39-62.

Bovine Health

 O’Connor AM, Yuan C, Cullen JN, Coetzee JF, da Silva N, Wang C. A mixed treatment meta-analysis of antibiotic treatment options for bovine respiratory disease – An update. Prev Vet Med. 2016;132:130-9.(doi):10.1016/j.prevetmed.2016.07.003. Epub  Aug 31.

Cullen JN, Yuan C, Totton S, Dzikamunhenga R, Coetzee JF, da Silva N, et al. A systematic review and meta-analysis of the antibiotic treatment for infectious bovine keratoconjunctivitis: an update. Anim Health Res Rev. 2016;17(1):60-75. doi: 10.1017/S1466252316000050

Buczinski S, O’Connor AM. Specific Challenges in Conducting and Reporting Studies on the Diagnostic Accuracy of Ultrasonography in Bovine Medicine. Vet Clin North Am Food Anim Pract. 2016;32(1):1-18. doi: 0.1016/j.cvfa.2015.09.009.

A systematic review and meta-analysis of the antibiotic treatment for infectious bovine keratoconjunctivitis: an update. Cullen JN, Yuan C, Totton S, Dzikamunhenga R, Coetzee JF, da Silva N, Wang C, O’Connor AM. Anim Health Res Rev. 2016 Jun;17(1):60-75. doi: 10.1017/S1466252316000050.

A mixed treatment meta-analysis of antibiotic treatment options for bovine respiratory disease – An update. O’Connor AM, Yuan C, Cullen JN, Coetzee JF, da Silva N, Wang C. Prev Vet Med. 2016 Sep 15;132:130-9. doi: 10.1016/j.prevetmed.2016.07.003. Review.

A critical review and meta-analysis of the magnitude of the effect of anthelmintic use on stocker calf production parameters in Northern US States. Baltzell P, Engelken T, O’Connor AM. Vet Parasitol. 2015 Nov 30;214(1-2):2-11. doi: 10.1016/j.vetpar.2015.09.019. Review. PMID: 26412143

O’Connor, A.M., Brace, S., Gould, S., Dewell, R., Engelken, T., 2011a. A randomized clinical trial evaluating a farm-of-origin autogenous Moraxella bovis vaccine to control infectious bovine keratoconjunctivis (pinkeye) in beef cattle. J. Vet. Intern. Med. 25, 1447-1453.

O’Connor AM, Coetzee JF, da Silva N, Wang C. A mixed treatment comparison meta-analysis of antibiotic treatments for bovine respiratory disease. Prev Vet Med. 2013;110(2):77-87. Epub 2013/01/02. doi: 10.1016/j.prevetmed.2012.11.025. PubMed PMID: 23276402.

Wellman, N.G., O’Connor, A.M., 2007. Meta-analysis of treatment of cattle with bovine respiratory disease with tulathromycin. J. Vet. Pharmacol. Ther.30, 234-241.

Burns, M.J., O’Connor, A.M., 2008. Assessment of methodological quality and sources of variation in the magnitude of vaccine efficacy: a systematic review of studies from 1960 to 2005 reporting immunization with Moraxella bovis vaccines in young cattle. Vaccine26, 144-152.

O’Connor AM, Gould SA, Coetzee JF, Kreuder AJ, Plummer PJ. What is the evidence? Intra-abdominal administration of antimicrobial drugs to prevent peritonitis or wound infection in cattle after abdominal surgery. J Am Vet Med Assoc. 2011;239(3):314-6. Epub 2011/08/02. doi: 10.2460/javma.239.3.314. PubMed PMID: 21801043.

O’Connor AM, Wellman NG, Rice M, Funk L. Characteristics of clinical trials assessing antimicrobial treatment of bovine respiratory disease, 1970-2005. J Am Vet Med Assoc. 2010;237(6):701-5. Epub 2010/09/16. doi: 10.2460/javma.237.6.701. PubMed PMID: 20839994.

Baltzell, P., Newton, H., O’Connor, A.M., 2013. A Critical Review and Meta-Analysis of the Efficacy of Whole-Cell Killed Tritrichomonas foetus Vaccines in Beef Cattle. J. Vet. Intern. Med. 2013 Jul-Aug; 27(4), 760-70.

Companion Animals

Intestinal cytokine mRNA expression in canine inflammatory bowel disease: a meta-analysis with critical appraisal. Jergens AE, Sonea IM, O’Connor AM, Kauffman LK, Grozdanic SD, Ackermann MR, Evans RB. Comp Med. 2009 Apr;59(2):153-62. Erratum in: Comp Med. 2009 Jun;59(3):220.  PMID: 19389307c

Support materials for EFSA AHAW panel on testing for canine Leishmania infantum infection. O’Connor, A., Dzikamunhenga, R.S., Wolfe, D., Sargeant, J., Glanville, J. and Wood, H., 2015. Preparatory work for the future development of scientific opinions on animal health. EFSA Supporting Publications12(2).

A systematic review and meta-analysis of the proportion of dogs surrendered for dog-related and owner-related reasons. Lambert K, Coe J, Niel L, Dewey C, Sargeant JM. Prev Vet Med. 2015 118(1):148-60. PMID: 25466216